A case-case study on the effect of primary and booster immunization with China-produced COVID-19 vaccines on prevention of pneumonia and viral load among vaccinated persons infected by Delta and Omicron variantsDelta 및 Omicron 변종에 감염된 백신 접종자의 폐렴 및 바이러스 부하 예방에 대한 중국산 COVID-19 백신의 1차 및 추가 접종 효과에 대한 사례 연구Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, [키워드] administration age analysed association booster booster dose booster immunization calculate case study case-case study COVID-19 COVID-19 outbreak COVID-19 pneumonia COVID-19 vaccine Ct value Ct values Delta determine eligible evaluated immunization Infection infections less Logistic regression no difference no differences Odds ratio Odds ratios omicron pace Pneumonia real-world study. recipient reduced reduction SARS-CoV-2 viral load vaccination Vaccination Status variant Viral load [DOI] 10.1080/22221751.2022.2103455 PMC 바로가기 [Article Type] Article
Advancement and Challenges of Biosensing Using Field Effect Transistors전계효과 트랜지스터를 이용한 바이오센싱의 발전과 과제Review Published on 2022-08-172022-09-11 Journal: Biosensors [Category] SARS, 치료기술, [키워드] accompanied advancement approaches biosensors carried challenge coronavirus coronavirus disease COVID-19 pandemic Debye Debye length degrade Detection sensitivity Device direction domain Effect effective faster field field effect transistors field-effect transistor functional functionalization mechanism Microarray Modification modifications pace Pathogens provided raised SARS-CoV-2 spike protein Screening sensitivity specificity specificity. Spike protein surface area the SARS-CoV-2 transistor Transport [DOI] 10.3390/bios12080647 PMC 바로가기 [Article Type] Review
Results of a European-Wide External Quality Assessment (EQA) Scheme for Serological Detection of Anti-SARS-CoV-2 (CoVimm)-Pitfalls of Routine ApplicationAnti-SARS-CoV-2(CoVimm)의 혈청학적 검출을 위한 유럽 전역 외부 품질 평가(EQA) 계획의 결과-일상 적용의 함정Article Published on 2022-07-282022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법, [키워드] addition Analysis analytical methods analytical techniques anti-S anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG antibody application assessment biospecimen clinically comparability COVID-19 detection differentiation EQA Europe External external quality assessment scheme external quality control harmonization heterogeneity IgG IgG antibodies IgG antibody immunoassays implication Interpretation introduced Laboratory lack measure new SARS-CoV-2 nucleocapsid pace participated proficiency testing Quality Quality assurance reliability reported Result routine routine care SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 virus serological Serological testing specific IgG antibodies Spike protein standard care Standardization test performance. test results thresholds total antibody variety virus [DOI] 10.3390/v14081662 PMC 바로가기 [Article Type] Article
Drug repurposing based on a quantum-inspired method versus classical fingerprinting uncovers potential antivirals against SARS-CoV-2고전적 지문과 비교하여 양자에서 영감을 받은 방법을 기반으로 한 약물 용도 변경은 SARS-CoV-2에 대한 잠재적인 항바이러스제를 밝혀냅니다.Article Published on 2022-07-182022-09-11 Journal: PLoS Computational Biology [Category] COVID19(2023년), SARS, 변종, 신약개발, 치료제, [키워드] accelerated Algorithm Alpha Antiviral antiviral therapeutics approach approved B.1.1.7 B.1.351 B.1.617.2 Beta binary BMS-986094 Cell culture classical cobalamin Combination comparison Comparisons complex complexity Compound compounds computational resource computational resources COVID-19 pandemic cytotoxicity Delta demonstrated Drug repurposing DrugBank database Efficacy England evaluate form GS-6620 IC50 identify in vitro inhibit inhibited inhibitors inhibitory concentration limit maximum optimization overlap pace parameter predicted problem RdRP Remdesivir replication of SARS-CoV-2 resolved RNA-dependent RNA polymerase SARS-CoV-2 SARS-COV-2 infection screening method several variant several variants strain these compound these compounds vitamin B12 while [DOI] 10.1371/journal.pcbi.1010330 PMC 바로가기 [Article Type] Article
A cautionary note on altered pace of aging in the COVID-19 era코로나19 시대 고령화 속도 변화에 대한 주의사항Article Published on 2022-07-012022-09-11 Journal: Forensic science international. Genetics [Category] COVID19(2023년), MERS, SARS, 바이오마커, 유전자 메커니즘, [키워드] accumulated acute respiratory syndrome Affect age aging all-cause mortality Alter Blood chronological age Clinical research CLOCK confounder Corona virus coronavirus disease Coronavirus disease 2019 COVID COVID-19 COVID-19 pandemic DNA methylation DNA methylation markers Effect Epigenetic Forensic Forensic age estimation heterogeneous nature Immune cell immune cells immune response individual individuals Interpretation joint life style management marker Modification modify molecular mortality risk pace pandemic pathogen Pathogens Pathologies pathology performed persistence Perturbation perturbations reliability Research respiratory risk SARS-CoV-2 SARS-CoV-2 pandemic scar Severe acute respiratory syndrome SjTREC syndrome T-cell receptor telomere Telomere length. the SARS-CoV-2 These data vaccination virus [DOI] 10.1016/j.fsigen.2022.102724 PMC 바로가기 [Article Type] Article
Going Retro, Going Viral: Experiences and Lessons in Drug Discovery from COVID-19레트로화, 바이럴화: COVID-19 약물 발견의 경험과 교훈Article Published on 2022-06-142022-09-11 Journal: Molecules [Category] Coronavirus, COVID19(2023년), SARS, 신약개발, 치료제, [키워드] active site Antibiotics binding binding site Cell culture Clinical use computational studies Computational study COVID-19 COVID-19 pandemic develop docking drug Drug discovery drug target effective effort enzyme experience fidaxomicin flexible implication improvement in silico in vitro inhibit inhibitors lesson Ligand ligands Mutagenesis NiRAN nucleotide nucleotide analogs pace pathogen Pathogens predicted protein complex protein complexes RdRP researcher rifabutin rifamycins. RNA synthesis RNA-dependent RNA polymerase SARS-CoV-2 SARS-CoV-2 RdRp severity silico studies speed Spread throughput viral replication Virtual screening [DOI] 10.3390/molecules27123815 PMC 바로가기 [Article Type] Article
How to accelerate the supply of vaccines to all populations worldwide? Part II: Initial industry lessons learned and detailed technical reflections leveraging the COVID-19 situation전 세계 모든 인구에 대한 백신 공급을 가속화하는 방법은 무엇입니까? 2부: COVID-19 상황을 활용한 초기 업계 교훈 및 상세한 기술적 반성Review Published on 2022-02-232022-09-11 Journal: Vaccine [Category] COVID19(2023년), SARS, 변종, 신약개발, [키워드] accelerate approaches benefit changes comparability COVID-19 COVID-19 pandemic COVID-19 situation Digital disease Diseases distribution feasible genetically modified organisms harmonization Health heterogeneity majority market offer organism pace Part pathogen Pathogens Population populations public health public health threat Quality control Regulatory Regulatory convergence Reliance Risk-based Science Science-based stability Streamline the vaccine Treatment vaccination Vaccine vaccine. Vaccines variants while [DOI] 10.1016/j.vaccine.2021.12.038 PMC 바로가기 [Article Type] Review
Digital Inclusion as a Foundation for Health Equity. Comment on “Expanding Video Consultation Services at Pace and Scale in Scotland During the COVID-19 Pandemic: National Mixed Methods Case Study”Letter to the Editor Published on 2022-02-032022-10-30 Journal: Journal of Medical Internet Research [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] Comment consultation COVID-19 Digital digital divide Digital health equity digital inclusion foundation General practice pace PERCS framework Quality improvement Remote Consultation scale Scotland service technology-enabled care video consultations [DOI] 10.2196/34702 PMC 바로가기 [Article Type] Letter to the Editor
Sustaining effective COVID-19 control in Malaysia through large-scale vaccination대규모 예방 접종을 통해 말레이시아에서 효과적인 COVID-19 통제 유지Article Published on 2021-12-012022-09-11 Journal: Epidemics [Category] SARS, 변종, 치료기술, [키워드] age change compartmental model competing Complete Control country Coverage COVID-19 COVID-19 cases death disease severity effective Epidemic Government highlighting ICU Infection intervals Intervention Malaysia Mathematical modelling movement National NPI NPIs pace population immunity Prevent proportion public health reduce Region resulting resurgence saturation severity Stratification stratified suggested susceptible the epidemic type strain vaccination vaccination rate Vaccination strategy Vaccine variants variants of concern variants of concern. wild-type strain [DOI] 10.1016/j.epidem.2021.100517 PMC 바로가기 [Article Type] Article
Reductionism Ad Absurdum: The Misadventures of Structural Biology in the Time of Coronavirus환원주의 Ad Absurdum: 코로나바이러스 시대의 구조생물학의 불행Article Published on 2021-11-122022-09-11 Journal: ACS Infectious Diseases [Category] SARS, 치료기술, 치료제, [키워드] analogues approach Biology characterization consequence Course COVID-19 pandemic detect exchange faster global scientific community mechanism misunderstanding nucleoside nucleoside analogue Nucleoside analogues pace RdRP recommendation Reductionism Remdesivir Research researcher response RNA polymerase RNA-dependent RNA polymerase SARS-CoV-2 SARS-CoV-2 RNA structural biology time [DOI] 10.1021/acsinfecdis.1c00492 PMC 바로가기 [Article Type] Article